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Manufacturers: Biosynthesis
Active ingredients
- Levorin
Disease class
- Changes in skin structure
- Carriage of the causative agent of another infectious disease
- Candidal stomatitis
- Candidiasis of the skin and nails
- Candidiasis of the vulva and vagina (N77.1*)
- Candidiasis of other localizations
- Cystitis
- Urethritis and urethral syndrome
- Vaginitis, vulvitis and vulvovaginitis in infectious and parasitic diseases classified elsewhere
Clinical and pharmacological group
- Antifungal antibiotics
Pharmacological action
- Antifungal
- Fungicidal
Pharmacological group
- Antifungal agents
Instructions for use
Each package contains a small receipt - instructions for use, necessary for safe, and most importantly, effective use. It contains information about the indications, method of administration, possibility of use during pregnancy and breastfeeding, drug interactions with this medicine, possibility of taking the medicine for kidney/liver disorders, side effects, contraindications, pharmacology, overdose, etc.
Pharmacology
This drug contains double bonds in large quantities. They are characterized by a high level of tropism for the formation of fungal membranes. The maximum activity of the drug is observed against bacteria such as Candida aldicans and a number of protozoa, for example, Trichomonas.
If the drug enters the human body, it is practically not absorbed from the gastrointestinal tract and is excreted through the intestines.
Indications
Gastroenterologists very often prescribe the drug Levorin for the treatment of candidiasis of the gastrointestinal tract (only the oral form of the drug is used). In addition, the drug Levorin can be prescribed for the treatment of cystitis, vulvovaginitis, urethritis (the drug is used only for topical use).
Levorin can be prescribed for the treatment of paronychia, lesions of skin folds, as well as erosion between the fingers (used for external use).
Mode of application
Dosage adjustment may be required for elderly patients. The tablets should be taken orally. For candidiasis of the gastrointestinal tract, adults should take 500 thousand units of the drug. The number of receptions is divided into 2-4 times. Treatment should be continued for 10 days. If the doctor considers it necessary, therapy can be increased to 12 days.
It is not recommended to take the medicine yourself.
For small children, the dosage is calculated based on the child’s age:
- For small children under 2 years of age, the recommended dosage is 25 thousand units/kg;
- If the child is from 2 to 6 years old, then the drug is prescribed at a dosage of 25 thousand units/kg per day;
- If the child is over 6 years old, then the drug is prescribed at a dosage of 200 thousand units per day.
The duration of therapy for children is usually a week. If required, treatment is repeated after a week (a general blood test is required). If taking the drug is accompanied by vomiting, the drug should be taken after meals.
Release form
For gastrointestinal diseases, you should take Levorin only in tablet form. The product contains levorin 500 thousand units.
Drug interactions
Before starting treatment, doctors still recommend warning your doctor about taking any medications. No data on the drug combination was provided.
LEVORIN has a detailed annotation in each package indicating all its properties and use.
Levorin oral tablets
Instructions for medical use of the drug
Description of pharmacological action
Active against yeast-like fungi (in particular, the genus Candida) and some protozoa (Trichomonas vaginalis). Does not have cumulative properties (the ability to accumulate in the body). Low toxic.
Indications for use
Diseases caused by the yeast-like fungus Candida: candidiasis of the gastrointestinal tract, lesions of the skin, mucous membranes, female genital organs, trichomoniasis of the genital organs; for prophylactic purposes in case of candidiasis (the presence of parasitic fungi in the body without the development of the disease).
Release form
tablets 500 thousand units; polymer jar (jar) 25 cardboard pack 1; tablets 500 thousand units; contour packaging 10 cardboard pack 2;
Pharmacokinetics
After oral administration, it is practically not absorbed from the gastrointestinal tract and is excreted in feces.
Use during pregnancy
Use with caution during lactation.
Contraindications for use
Hypersensitivity; for oral administration - liver and/or renal failure, acute gastrointestinal diseases of non-fungal etiology, pancreatitis, gastric and duodenal ulcers, pregnancy.
Side effects
When taken orally: loss of appetite, dyspeptic symptoms (nausea, vomiting, diarrhea, abdominal pain), headache, allergic reactions (itching), dermatitis. Local irritant effect.
Directions for use and doses
Inside. For gastrointestinal candidiasis and intestinal candidiasis, adults are prescribed 500 thousand units 2-4 times a day for 10-12 days. Children under 2 years old - 25-30 thousand units/kg/day, 2-6 years old - 20-25 thousand units/kg/day, over 6 years old - 200-250 thousand units 2-4 times a day day.
Precautions for use
Severe side effects require discontinuation of treatment. In case of nausea or vomiting, the drug is taken after meals. The functional state of the liver should be monitored.
Special instructions for use
Use with caution in children under 2 years of age. With prostate hypertrophy, levorin reduces dysuric phenomena, and in some cases, the size of the adenoma. It is believed that it is possible to use levorin as part of complex therapy for prostate hypertrophy.
Storage conditions
List B.: In a dry place, protected from light, at a temperature not exceeding 5 °C.
Best before date
24 months
ATX classification:
D Dermatotropic drugs
D01 Antifungal drugs for the treatment of skin diseases
D01A Antifungal drugs for external use
D01AE Other antifungal preparations for external use
Side effects
The patient’s body can give a response, which is usually expressed in diseases and conditions such as:
- Vomiting, headache, diarrhea, dizziness, nausea, as well as pain in the abdomen, loss of appetite;
- Hives, itching, redness of the skin, swelling of the face.
Overdose
In the event of an overdose, a person experiences symptoms such as:
- Head pain, dizziness;
- Diarrhea, vomiting, constipation;
- Decreased appetite;
- Fever, chills, heat;
- Severe itching, redness of the skin;
- Irritation.
If you have signs of an overdose, you need to stop taking the drug. Next, the patient is advised to go to the hospital to receive medical care.
Contraindications
A drug belonging to the group of polyenes.
It is not recommended to take this medicine if you have such concomitant diseases and conditions as:
- Severe form of liver or kidney failure;
- Pancreatitis;
- Stomach ulcer;
- Acute diseases of the gastrointestinal tract;
- Duodenal ulcer.
Caution: Levorin can be prescribed for mild to moderate renal or liver failure. In addition, the medicine is carefully prescribed for the treatment of young patients under 2 years of age.
Pregnancy period
If it is impossible to stop the drug, then taking it is allowed, however, the girl must always be under the supervision of a doctor, i.e. stay in hospital. Only such a measure will allow monitoring the negative impact on the fetus.
During breastfeeding you should refrain from taking the medicine. If it is not possible to replace the drug Levorin with a safe analogue, then taking the drug is allowed, however, before starting treatment, the issue of stopping breastfeeding must be decided.
Similar drugs:
- Natamycin Substance-powder
- Lamisil Uno Topical solution
- Livarol Vaginal suppositories
- Lamisil Oral tablets
- Mycocet Ointment for external use
- Loceryl Solution for local and external use
- Lotrimin Cream for external use
- Fluomisin Vaginal tablets
- Primafungin Vaginal suppositories
- Candibene Vaginal tablets
** The Drug Directory is intended for informational purposes only. For more complete information, please refer to the manufacturer's instructions. Do not self-medicate; Before starting to use Levorin, you should consult a doctor. EUROLAB is not responsible for the consequences caused by the use of information posted on the portal. Any information on the site does not replace medical advice and cannot serve as a guarantee of the positive effect of the drug.
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** Attention! The information presented in this medication guide is intended for medical professionals and should not be used as a basis for self-medication. The description of the drug Levorin is provided for informational purposes and is not intended for prescribing treatment without the participation of a doctor. Patients need to consult a specialist!
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special instructions
In this section you can find useful information.
Driving
The medicine may affect the driver while driving.
Pregnancy
During pregnancy, you should refrain from using this drug. During pregnancy, it is highly undesirable to take Levolin. This is due to the fact that the active substance can have a detrimental effect on the fetus.
It is also not recommended to take this drug while breastfeeding.
Admission in childhood
This drug can be taken from 2 years of age.
Use for kidney problems
Taking the drug is contraindicated if kidney function is damaged.
Use for liver dysfunction
Taking the medication is contraindicated if the liver function is impaired.
Release from pharmacy
Only by prescription from a doctor.
Medicine and alcohol
Taking medication and alcohol are two incompatible things.
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Storage
The drug Levorin must be placed in a room where the temperature is from 0 to 5 degrees. In addition, this room should be dark and dry. The room should also be cool (the drug is usually stored in the refrigerator).
If these conditions are met, Levorin can be taken for two years. After the expiration date, further use of the medicine is strictly prohibited. The medicinal product must be disposed of by placing it in the trash.
Trade name: ZALAIN®
International nonproprietary name: Sertaconazole
Dosage form: vaginal suppositories
Composition for 1 suppository
Active ingredient: sertaconazole nitrate 300 mg; excipients: vitepsol 1.305 g, suppotsir 1.305 g, colloidal anhydrous silicon dioxide 0.09 g.
Description: oval-shaped, waxy, white suppositories.
Pharmacotherapeutic group: antifungal agent
ATX code: G01AF
PHARMACOLOGICAL PROPERTIES
Sertaconazole is an antifungal agent derived from imidazole and benzothiophene. It has fungistatic and fungicidal effects in therapeutic doses. Active against fungi of the genus Candida. The mechanism of action of sertaconazole is to inhibit the synthesis of ergosterol and increase the permeability of the fungal cell membrane, which leads to lysis of the fungal cell.
It also has antibacterial activity against gram-positive bacteria (staphylo- and streptococci).
PHARMACOKINETICS
There is no absorption after intravaginal use.
INDICATIONS FOR USE
Local treatment of infections of the vaginal mucosa caused by fungi of the genus Candida (vulvovaginal candidiasis).
If necessary, please consult your doctor before taking the medicine.
CONTRAINDICATIONS
Hypersensitivity to imidazole derivatives, benzothiophene and other components of the drug.
Pregnancy and lactation
There are no sufficient data on the use of sertaconazole during pregnancy and lactation. However, taking into account the method of administration of the drug (single administration), as well as the lack of systemic absorption of the drug after intravaginal administration, the use of sertaconazole during pregnancy and lactation is possible if the potential benefit to the mother outweighs the possible risk to the fetus or child .
If necessary, please consult your doctor before taking the medicine.
METHOD OF APPLICATION AND DOSES
Intravaginally, once.
Before using the drug, you must wash the external genitalia using neutral or alkaline soap.
One vaginal suppository is inserted deep into the vagina, lying on your back, before bed.
If clinical symptoms persist, the suppository may be reintroduced after 7 days.
Use the drug only according to the method of use and in the doses indicated in the instructions.
If necessary, please consult your doctor before taking the medicine.
SIDE EFFECT
Rarely: burning sensation, itching in the vagina, which disappear on their own during treatment and do not require discontinuation of the drug. These side effects are classic for topical medications and reflect the effectiveness of the drug. Allergic reactions are possible.
Consult your doctor if you experience any of the side effects mentioned or other side effects not listed above.
OVERDOSE
Not installed.
If you accidentally take the drug orally, you must rinse your stomach and consult a doctor immediately.
INTERACTION
Simultaneous use of the drug with local contraceptives may lead to a weakening of the spermicidal effect of the latter.
SPECIAL INSTRUCTIONS
In case of simultaneous infection of the labia and adjacent areas (candidal vulvitis), additional local treatment with ZALAIN cream should be carried out.
When using the drug, it is recommended to abstain from sexual intercourse.
To prevent urogenital reinfection, it is recommended to consider simultaneous treatment of the sexual partner.
The risk of condom or diaphragm rupture increases when used simultaneously with the drug.
Treatment can be carried out during menstruation.
Zalain does not affect the performance of potentially hazardous activities that require special attention and quick reactions (driving a car, etc.).
STORAGE CONDITIONS
At a temperature not exceeding 30 C. Keep out of the reach of children.
Best before date
5 years. Do not use after the expiration date stated on the packaging.
Release form
Vaginal suppository 300 mg.
1 vaginal suppository in a PVC/PE blister. 1 blister along with instructions for use in a cardboard box.
Conditions for dispensing from pharmacies
Over the counter.
Registration Certificate Holder
CJSC Pharmaceutical Plant EGIS, Hungary
1106 Budapest, st. Kereszturi ut 30-38 (1106 Budapest, Kereszturi ut 30-38, Hungary)
Phone: (36-1) 803-5555,
Fax: (36-1) 803-5529
Under license from Ferrer International A.O., Spain
Manufacturer
Trommsdorff GmbH and Co. KG, Germany, Trommsdorffstrasse 2-6, 52477, Alsdorf (Trommsdorffstrasse 2-6, 52477, Alsdorf, Germany) (all stages of production);
CJSC Pharmaceutical Plant EGIS, Hungary
1165, Budapest, st. Bokenyfoldi 118-120 (1165 Budapest, Bokenyfoldi ut 118-120, Hungary) (quality control issuer)
Name and address of the organization authorized by the holder or owner of the registration certificate of the medicinal product to accept claims from the consumer
LLC "EGIS-RUS", Russia
121108, Moscow, st. Ivana Franko, 8, phone: (495) 363-39-66
Price
To clarify the price, you need to contact a specific pharmacy or online store. The instructions provide an approximate cost.
In Russia and Ukraine the price will differ significantly. This is due to the exchange rate and currency.
Russia
For the drug Levorin you will have to pay up to 129 rubles.
Ukraine
The medicine Levorin costs on average 59 hryvnia.
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Reviews
Reviews about this medicine are usually positive. This is due to the high effectiveness of the product. In addition, among the positive reviews, people note the convenient method of administration. The drug also has a low cost, which does not put a strain on citizens’ pockets. On the forums you can find reviews not only from patients, but also from specialists who are aware of the peculiarities of taking the medicine.
Doctors note that in 90% of cases the drug has the expected effect. You can also find neutral reviews from specialists on the Internet. Doctors note the lack of effect due to improper use of the drug. The drug Levorin has a number of negative aspects, among which it is noted that the drug is quite difficult to get at the pharmacy, as well as the presence of a large number of contraindications.
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