Gel Metrogyl Denta and its budget analogues

pharmachologic effect

Manufacturer: Unique Pharmaceutical Laboratories, India
Release form: dental gel

Active ingredient: chlorhexidine, metronidazole

Synonyms: Metrodent, Dentamet

Metrogyl Denta is a combined agent that exhibits antimicrobial, cooling and weak local anesthetic effects. This gel effect is due to the components included in the composition.

Chlorhexidine is an antiseptic substance that exhibits a bactericidal effect and is active against bacteria and some viruses.

Metronidazole is an antiprotozoal and antimicrobial substance that is active against anaerobic bacteria.

Levomenthol is an auxiliary component that exhibits local analgesic and anti-inflammatory effects.

Metrogyl Denta - instructions for use

According to the instructions for use, Metrogyl Denta gel is used topically in adults and children over 6 years of age.

The dosage regimen of the medication depends on the patient’s condition:

• For stomatitis, the drug is applied 2 times a day for 7–10 days.
• For gingivitis, the medicine is applied to the gums 2 times a day for 7–10 days.
• In case of inflammation of the tissues around the tooth, the drug is applied in a thin layer twice a day. The course of treatment is 1–2 weeks.
• After tooth extraction, the medication is placed in the hole 2-3 times a day. Treatment continues for 7 days.
• As a prophylaxis for chronic gum inflammation, apply twice a day for 10 days. Such prevention is carried out once every six months.

After applying the drug, do not eat or drink for 30 minutes.

What kind of drug?

This drug is produced in the form of a gel in an aluminum tube of 20 grams.

Metrogyl Denta is an antimicrobial dental gel that is used in complex therapy and as preventive measures for certain types of inflammatory pathologies of the oral cavity of infectious etiology.

The pharmacological effect of the drug is to destroy pathogenic microorganisms.

This effect is exerted by active ingredients such as chlorhexidine digluconate and metronidazole.

This drug is produced in the form of a gel in an aluminum tube of 20 grams, packed in a cardboard box with instructions for use.

The use of Metrogyl Dent is recommended for diseases of inflammatory and infectious etiology.

High therapeutic effectiveness is observed in the treatment of:

• Periodontal disease.
• Heilita.
• Pulpitis.
• Aphthous stomatitis
• Candidal stomatitis
• Abscesses
• Gingivitis
• Alveolitis
• Mechanical injury to the mucous membrane.

Important! The regimen for using the drug depends on the type and degree of development of the pathology. Therefore, its appointment should be carried out exclusively by a dentist after a full examination.

The cost of the drug in pharmacies varies between 216 rubles per tube of gel.

Metrogil Dent's analogs

For the treatment of infectious and inflammatory diseases of the oral cavity, Metrogyl Denta and its analogs are used, which differ in composition, mechanism of action and release form.

List of analogues of Metrogyl Denta with prices

Metrogyl or Metrogyl Denta - which is better?

Manufacturer: Unique Pharmaceutical Laboratories, India
Release form: gel for external use

Active ingredient: metronidazole

Synonyms: Rozamet, Rozeks

Metrogyl gel is an analogue of Metrogyl Dent, produced by one pharmaceutical company. The medication contains metronidazole, which exhibits antimicrobial and antiprotozoal effects. Metrogyl is used for acne, bedsores, burns, ulcers, cracks and other lesions of the skin and mucous membrane.

The analogue is applied to the affected areas twice a day. The course of treatment is up to 9 weeks.

It is impossible to say which drug is better. Metrogyl Denta and its analogue have a similar composition and mechanism of action, but have different indications for use.

Metrogyl Denta: characteristics of the drug

This is a well-known medicine that helps in the fight against infectious and inflammatory diseases of the oral cavity. This product is sold over-the-counter in pharmacies.

Metrogyl Denta is a gel based on chlorhexidine and metronidazole. Chlorhexidine is an antiseptic that prevents the proliferation of pathological microorganisms on the mucous membrane. It is often used after surgery. Metronidazole is an active antibacterial agent widely used for periodontal diseases and oral mucosa.

Metrogyl Denta: how to use correctly

This drug, regardless of the inflammatory process in the oral cavity, is used according to the following scheme: apply a thin layer to the gums using a finger (after washing your hands) or a cotton swab - 2 times a day. After which it is not recommended to eat or drink for about 30 minutes. On average, the course of treatment is up to 10 days.

Metrogyl Denta: contraindications

The active substances included in this medicine have their own characteristic contraindications:

• allergic manifestations to metronidazole or chlorhexedine;
• diseases of the hematopoietic system;
• disorders of the nervous system;
• age under 18 years.

Therefore, before using this remedy, you need to consult a doctor.

Metrogyl Denta or Dentamet – which is better and more effective?

Manufacturer: JSC Altaivitaminy, Russian Federation
Release form: dental gel

Active ingredient: chlorhexidine, metronidazole

Dentamet is a cheap Russian analogue of Metrogil Dent. The drugs contain the same substances, but different amounts. Dentamet gel exhibits antiseptic and antiprotozoal effects. The analogue is used for infectious and inflammatory diseases of the oral mucosa.

The medication is applied in a thin layer to the affected areas 2-3 times a day for a week.

The advantages and disadvantages of the original product and its analogue are shown in the table.

The analogue is significantly inferior to the original drug. However, if the question is what can cheaply replace Metrogyl Dent for an adult, then the optimal remedy would be Dentamet.

Metrogil Denta or Dentamed?

Volume and form of release

Metrogyl Denta is produced in the form of a gel in a package with a tube of 20 grams, just like the drug Dentamed, but the volume of the latter is 20% larger and amounts to 25 grams.

In terms of gel consistency, Metrogyl Denta is superior to its competitor, as it has a denser structure and adheres well to the oral mucosa. Dentamet's texture is slightly softer (water content 86.28 g/100 g).

20 g

Compositions

Both drugs contain 2 active ingredients for the treatment of oral infections: chlorhexedine (20%) and metronidazole.

1. Chlorhexedine is a universal antiseptic that is often used to treat mucous membranes due to the lack of irritation, unlike, for example, alcohol. The downside is that if taken orally carelessly, it is quite toxic to the liver, so it is important to try not to swallow the medicine.
2. Metronidazole gives an excellent antibacterial effect against periodontitis and other diseases of the oral cavity caused by microorganisms sensitive to it and some protozoa. Its spectrum of action is wide and affects almost all typical pathogens of the oral cavity.

The difference between the opponents is in the composition of the excipients, which provide not only consistency, but also organoleptic (taste and smell) properties. Dentamet additionally contains menthol, which gives a characteristic aroma and a “cooling” effect. True, this may be unnecessary if you are prone to allergies, in which case it is better to opt for Metrogyl.

Application of Metrogyl Denta and dosage:

• For gingivitis, apply the gel with your fingertips or a stick with cotton at the end. The gel is applied to the affected areas and gums up to 2 times a day; it is recommended to keep it for up to half an hour, without rinsing or rinsing the mouth.
• To treat periodontitis, the gel is kept on the affected areas for up to half an hour, also up to 2 times a day. The gel is used for a week, in advanced cases 10 days.

Use of Dentamet and dosage:

• For the prevention and treatment of gingivitis (inflammation), apply topically to the affected mucosa 2 times a day, morning and evening. It is recommended to keep it for half an hour.
• Dentamed for stomatitis is also applied 2 times a day. It is recommended to carry out the procedure within a week or 10 days.

Expiration dates

An important criterion for those who are going to keep one of these products in their home medicine cabinet. Dentamed ointment has a shelf life of up to 2 years, Metrogyl Denta up to 3 years.

Price

Metrogyl Denta is produced in India, and Dentamet is a product of the Russian pharmaceutical factory Altaivitamin. In many ways, this is what accounts for the almost double advantage of the domestic analogue, despite the larger volume of the tube.

Metrogyl Denta gel or Cholisal - which is better and more effective for gum inflammation

Manufacturer: Elfa, Poland
Release form: dental gel

Active ingredient: choline salicylate, cetalkonium chloride

Cholisal is an analogue of Metrogil Dent for children from 1 year and adults. The medicine exhibits anti-inflammatory, antimicrobial and local analgesic effects. This effect of the drug is due to its constituent components. Cholisal is indicated for the following conditions:

• pain during teething in children and adults;
• inflammation of the oral mucosa;
• periodontitis;
• gingivitis;
• fungal infections of the oral cavity;
• conditions after surgical interventions.

The analogue is applied 2-3 times a day, after application it is necessary to refrain from taking liquids and food.

The possibility of use in children from 1 year and anti-inflammatory effect are the main advantages of Cholisal.

Both medications are used for gum inflammation. They do not interact with other drugs or hygiene products. If the inflammatory process is accompanied by bleeding and pus, then it is preferable to choose a medication based on chlorhexidine and metronidazole.

Comparison of side effects of Metrogil denta and Dentamet

Side effects or adverse events are any adverse medical event that occurs in a subject after administration of a drug.

Metrogil dents have almost the same level of adverse events as Dentamet. They both have few side effects. This implies that the frequency of their occurrence is low, that is, the indicator of how many cases of an undesirable effect of treatment are possible and registered is low. The undesirable effect on the body, the strength of influence and the toxic effect of Metrogyl dents are similar to Dentamet: how quickly the body recovers after taking it and whether it recovers at all.

Metrogyl Denta or Solcoseryl - which is better

Manufacturer: Legacy Pharmaceuticals, Switzerland
Release form: paste

Active ingredient: standardized deproteinized dialysate, polidocanol 600

Solcoseryl dental paste is an imported analogue of Metrogyl Denta gum gel. This paste is a combined preparation that includes a standardized deproteinized dialysate and polidocanol 600. These substances accelerate tissue healing and exhibit a local analgesic effect.

Solcoseryl is used for rapid healing of mucous membranes in cases of stomatitis, acute and indolent periodontitis, and gingivitis.

The analogue is applied after meals and before bedtime 3-5 times a day. Treatment continues until symptoms disappear.

A comparison of Metrogil Dent and its analogue is shown in the table.

The optimal drug for treatment depends on the condition, accompanying symptoms and the age of the patient.

Cheap analogues of Metrogyl Denta gel and their prices

In rare cases, Metrogyl may not have a therapeutic effect. It depends on the individual characteristics of the human body.

In this case, it can be replaced with other drugs. Metrogyl analogues can also be used to reduce the cost of a therapeutic course.

The best substitutes and how much they cost:

Important! The effectiveness of Metrogyl analogues depends on the correct use of them and combination with other drugs. Therefore, only a dentist should select generics for adults and children.

What is the best substitute, what analogues are the cheapest, most effective in Russia Among the most accessible generics of Metrogil Dent, herbal preparations for irrigating the oral cavity, made on the basis of plant components, stand out.

Among them, the greatest therapeutic effect is:

• Rotokan.
• Stomatophyte.
• Calendula extract.
• Ambassador
• Romazulan.

The medicinal composition of such drugs is enriched with biologically active natural components, which can have not only a therapeutic effect.

As a result of the use of such medications, there is a high probability of an allergic reaction to the constituent components. Therefore, before using them, it is necessary to conduct a preliminary allergy test.

Analogues made from synthetic chemical components are a little more expensive. But, such drugs have a quick positive effect in the treatment of periodontal diseases and oral mucosa.

In addition, such drugs effectively relieve acute symptoms of the pathology and reduce the duration of therapy.

Popular and affordable generics of Metrogil Dent include:

• Metrodent.
• Hexoral.
• Dentamet.
• Stomolik.
• Metrozol Denta.

Important! Regardless of the composition of the drug, its purchase should only be made in pharmacies. Since pharmacological agents require special storage conditions, failure to comply with which will deteriorate their therapeutic properties.

Metrogyl Denta or Asepta - which is better?

Manufacturer: Vertex, Russian Federation
Release form: gum balm

Active ingredients: chlorhexidine, metronidazole, mint, menthol

Asepta is a Russian substitute for Metrogil Dent. The balm has a similar composition and has an antimicrobial and anti-inflammatory effect, and is active against bacteria, yeast and some viruses.

The analogue is used for infectious and inflammatory diseases of the oral mucosa. The product is applied to problem areas 2-3 times a day for 7-10 days. The duration of the therapeutic effect is about 75 minutes.

For a faster recovery, it is recommended to additionally use Asepta gel based on propolis.

The choice of remedy is determined by the doctor’s prescription, condition, age and personal preferences of the patient.

Comparison of addiction between Metrogil denta and Dentamet

Like safety, addiction also involves many factors that must be considered when evaluating a drug.

So, the totality of the values ​​of such parameters as “syndrome o” in Metrogil denta is quite similar to the similar values ​​in Dentamet. Withdrawal syndrome is a pathological condition that occurs after the cessation of intake of addictive or dependent substances into the body. And resistance is understood as initial immunity to a drug; in this it differs from addiction, when immunity to a drug develops over a certain period of time. The presence of resistance can only be stated if an attempt has been made to increase the dose of the drug to the maximum possible. At the same time, in Metrogil denta the meaning of the “syndrome” is quite small, however, the same as in Dentamet.

Metrogil Denta or Kamistad – which is better?

Manufacturer: Stada Arzneimittel AG, Germany
Release form: gel for topical use

Active ingredient: lidocaine hydrochloride monohydrate, chamomile flower extract

Kamistad is a foreign analogue of Metrogyl Denta gel. The drug has a combined composition and exhibits a local anesthetic effect, relieves inflammation, and accelerates healing. The analogue is used for severe pain that is accompanied by teething in adults, wearing braces or dentures, stomatitis, gingivitis and other conditions.

Kamistad is applied in a thin layer to the affected areas three times a day. The duration of treatment depends on the condition.

The advantages and disadvantages of the medicine and its analogue are shown in the table.

Kamistad eliminates the symptoms of the disease, rather than fighting the infection. Therefore, for stomatitis, gingivitis and other inflammatory processes, it is advisable to use a combination of Metrogyl Dent and the Kamistad analogue.

Comparison of the safety of Metrogil denta and Dentamet

The safety of a drug includes many factors.

At the same time, in Metrogil denta it is quite similar to Dentamet. It is important where the drug is metabolized: drugs are excreted from the body either unchanged or in the form of products of their biochemical transformations. Metabolism occurs spontaneously, but most often involves major organs such as the liver, kidneys, lungs, skin, brain and others. When assessing the metabolism of Metrogyl Dents, as well as Dentamet, we look at which organ is the metabolizing organ and how critical the effect on it is.

The risk-benefit ratio is when the prescription of a drug is undesirable, but justified under certain conditions and circumstances, with the obligatory observance of caution in use. At the same time, Metrogil denta does not have any risks when used, just like Dentamet.

Also, when calculating safety, it is taken into account whether only allergic reactions occur or possible dysfunction of the main organs. In other matters, as well as the reversibility of the consequences of using Metrogil denta and Dentamet.

Chlorhexidine

Manufacturer: Ivanovo Pharmaceutical Factory, Russian Federation
Release form: solution for local and external use

Active ingredient: chlorhexidine

Chlorhexidine is a cheap analogue of Metrogil Dent in Russia. The drug exhibits an antiseptic effect and is active against bacteria, viruses and fungi. The solution is used in gynecology, urology, surgery. In dentistry, Chlorhexidine is used to treat stomatitis, alveolitis, and gingivitis.

The analogue is used in the form of applications or irrigations 2-3 times a day.

Comparison of the effectiveness of Metrogil denta and Dentamet

Dentamet is more effective than Metrogyl denta - this means that the ability of the medicinal substance to provide the maximum possible effect is different.
For example, if the therapeutic effect of Dentamet is more pronounced, then with Metrogyl dents it is impossible to achieve this effect even in large doses.

Also, the speed of therapy is an indicator of the speed of the therapeutic action; Dentamet and Metrogil dents are also different, as is bioavailability - the amount of a medicinal substance reaching the place of its action in the body. The higher the bioavailability, the less it will be lost during absorption and use by the body.